By Susan M. Callahan, Associate Editor and Featured Columnist
Preeclampsia is a condition that occurs during pregnancy that is characterized by high blood pressure and the presence of proteins in your urine. Preeclampsia usually occurs, if at all, after the 20th week of pregnancy.
Also known as “toxemia” or inaccurately called “pregnancy related hypertension”, preeclampsia was first identified over 2000 years ago by the Roman medical writer Aulus Cornelius Celsus, who observed mysterious deadly seizures among pregnant women. These seizures appear much like epileptic fits, with loss of consciousness and frothing at the mouth.
Left untreated, preeclampsia can lead to eclampsia, with serious complications including seizures, blood clots (thrombosis), accumulation of fluid in the lungs (pulmonary edema), coma, kidney failure, brain damage and death.
According to the U.S. Department of Health and Human Services, approximately 3 to 8 % of all pregnant women in America experience preeclampsia and high blood pressure (hypertension), a precondition of preeclampsia, accounts for almost 15% of deaths among pregnant women. Worldwide, more than 33% of women with preeclampsia die during childbirth or shortly after delivery.
Once diagnosed with preeclampsia, you face a higher risk of miscarriage. Even after you deliver, preeclampsia puts you at a higher risk for heart disease for the remainder of your life.
Preeclampsia is different from simple high blood pressure during pregnancy. High blood pressure is a symptom of preeclampsia. You can have high blood pressure without also having preeclampsia. But merely having high blood pressure is a serious condition for pregnant women. If you have high blood pressure during your pregnancy, you are at a high risk for hypertension following delivery.
Because preeclampsia is a different condition from simple high blood pressure, the treatments are different. Medicines and foods which help to reduce high blood pressure, such as garlic, have no effect whatsoever on reducing your risk for preeclampsia or reducing preeclampsia symptoms. And vice- versa, the foods which reduce your risk for preeclampsia are not the typical foods that lower blood pressure.
What foods reduce preeclampsia risk? What type of diet lowers your risk for developing high blood pressure during pregnancy? Based upon research studies, here are the foods that reduce the risk for preeclampsia and high blood pressure during pregnancy:
1. Calcium Reduces Preeclampsia Risk by 50%. Calcium and calcium-rich foods reduce your risk for preeclampsia. A landmark 2006 study jointly conducted by researchers from the University of the Witwatersrand and the University of Fort Hare in South Africa found that calcium supplementation cuts the risk of pre-eclampsia by 50%. The study examined the records of nearly 15,000 women who took 1 gram (1000 milligrams) of calcium daily. Not only was pre-eclampsia risk cut in half but the risk that the children would later develop childhood hypertension was also reduced significantly.
What foods should you include in your diet to reduce preclampsia risk? Calcium-rich foods include milk, sardines, low-fat cheese, mackerel and yogurt. For breakfast, try a yogurt parfair topped with strawberries.
2. Vitamin C and E May Help to Reduce Preeclampsia. Here, the evidence is mixed. One 2002 study from King’s College in London caused excitement in the medical community when it reported that Vitamin C supplements appeared to reduce pre- eclampsia risk. In this study, women were given 1000 mg of Vitamin C and 400 IU’s (international Units) of Vitamin E each day.
The study examined 3 groups of women. The first two groups ---one of 79 women and another of 81 women – were both at high risk for preeclampsia. The third group of 32 women was at low risk for preeclampsia. Only one of the high risk groups was given the Vitamin C and Vitamin E supplements. At the end of the study, researchers found that the group of high-risk women who had taken Vitamin C and E supplements had almost identical blood chemistries to the healthy group of low-risk women. The "bad" biological markers for preeclampsia , such as plasminogen activator inhibitor-2, and placenta growth factor concentrations decreased; and "good" markers such as 8-epi-prostaglandin F(2alpha), leptin, and the plasminogen activator inhibitor increased.
However, later attempts to replicate these results produced opposite conclusions. In these later studies, one of which was conducted in 2009 by Oxford University researchers under the auspices of the World Health Organization, Vitamin C and E supplementation had no effect on pre-eclampsia risk. That study found “Supplementation was not associated with a reduction of pre-eclampsia , eclampsia, gestational hypertension, nor any other maternal outcome. “
Bottom line? For now, the evidence is inconclusive on the effectiveness of Vitamin C supplementation for lowering pre- eclampsia risk. The good news is that there is no downside to keeping your Vitamin C and E levels adeaquet and you could possibly reduce your risk of preeclampsia.
Try adding bellpeppers to your diet. Bellpeppers have a higher concentration of Vitamin C than oranges.
3. Garlic Lowers Blood Pressure in General but Doesn’t Help Preeclamsia. Garlic helps to lower blood pressure in women with hypertension. However, a study from the University of Liverpool in 2006 found that garlic has no effect whatsoever on preeclampsia risk.
4. These Foods Don't Appear to Interfere with Recommended Treatment for Chronic Hypertension in Pregnancy. In the U.S., physicians often recommend alpha- methyldopa to counter hypertension during pregnancy. This treatment is prescribed because typical antihypertensive medications may be unsafe for pregnant women.
You’ve heard of “ACE inhibitors”, the angiotensin-converting enzymes now popular for treating hypertension. These are not recommended for women who are pregnant. So, if you already have high blood pressure before you become pregnant, you will need to discuss a possible medication change with your doctor.
Supplementation with calcium, Vitamin C or Vitamin E has not been found to interfere with alpha-methyl dopa. But, as in all cases where you are taking doctor-prescribed medicaations, check first with your doctor before changing your diet.
4. Essential Minerals May Reduce Preeclampsia Risk. One important study in 1995 conducted by the Collaborative Eclampsia Trial found that women who took magnesium sulfate had a 52% lower risk of recurrent seizures and a 26% lower risk of maternal death than women on other prescribed medication (diazepam or phenytoin).
A separate study of magnesium, calcium and zinc’s link to preeclampsia confirmed that the levels of these essential minerals is low in women with preeclampsia as compared with the levels found in the blood of healthy pregnant women. This study suggested that supplementation with magnesium, calcium and zinc may significantly reduce preeclampsia risk.